Jimmy Fallon and Jamie Lee Curtis Send Up Nathan Fielder and Elizabeth Holmes in Tonight Show Cold Open

The Tonight Show opened on Wednesday with a sketch that paired Jimmy Fallon and Jamie Lee Curtis in a short satirical piece. Fallon assumed the persona associated with Nathan Fielder, while Curtis appeared as Elizabeth Holmes. The sequence was built around the programme’s cold open — a brief, standalone punch that precedes the episode’s main monologue — and relied on a single, focused back-and-forth between the pair. Reports framed the sketch as a deliberate reworking of the 'You Can See Everything' concept, presenting the exchange as the night’s initial offering before the show moved on to its regular segments.

In the sketch Fallon adopted the offbeat, investigative tone associated with Nathan Fielder, using that approach to question Jamie Lee Curtis’s character. The interaction centred on Fallon’s grilling of Curtis-as-Holmes, with the host maintaining a straight-faced, probing style. Coverage noted Fallon’s turn as firmly in keeping with earlier send-ups of real-life oddities, and it came from a presenter who has collected multiple Emmy Awards; Fallon is a six-time Emmy winner. The piece emphasised the contrast between Fallon’s reserved interrogator and Curtis’s portrayal of a high-profile figure.

Jamie Lee Curtis took on the role of Elizabeth Holmes for the cold open, committing to the sketch’s premise and the tight format of television parody. Curtis’s participation framed the exchange, allowing Fallon to steer the conversation with a questioning tone. Reports characterised the duo’s performance as an effective parody of the source material, and the sketch made use of the short-form comedy approach typical of Tonight Show cold opens: a crisp, focused scene designed to land quickly and send the episode off on a humorous note.

The Tonight Show sketch explicitly referenced 'You Can See Everything', the framework around which the parody was constructed. That choice tied into the show’s broader preparations for Halloween-themed content, with this cold open presented as part of the seasonal lead-up. Rather than expanding into a lengthy sketch, the piece concentrated on encapsulating the particular dynamic between a probing interviewer and a high-profile subject, offering viewers a short, topical satire that matched the timing of the holiday period.

The parody aired during Wednesday’s episode of The Tonight Show on NBC, appearing as the programme’s cold open before the episode’s main segments. The Tonight Show, broadcast on NBC, routinely opens with a short sketch or sequence, and this particular instalment featured Fallon and Curtis in the two central roles. The timing aligned with the run-up to Halloween, as the show added seasonal flavour to its regular line-up.

Media accounts described the pairing as a well-executed take on the subject, highlighting the chemistry between Fallon and Curtis within the sketch’s confined structure. The coverage focused on the cold open’s premise — Fallon adopting a Fielder-esque approach and Curtis portraying Holmes — and positioned the piece within the Tonight Show’s Halloween-related programming. Beyond the sketch itself, reports noted Fallon’s standing as an Emmy-winning host, underscoring the profile he brings to such moments on the programme.